Isomannide Dinitrate

• CAT Number: C000694
• CAS Number: 551-43-9
• Molecular Formula: C₆H₈N₂O₈
• Molecular Weight: 236.14
• Purity: ≥95%
• Synonyms: (3R,3aS,6R,6aS)-3,6-Bis-nitrooxy-hexahydro-furo[3,2-b]furan; (3R,3aS,6R,6aS)-Hexahydrofuran[3,2-b]furan -3,6-diyl Dinitrate
• Solubility: Chloroform (Soluble), Ethyl Acetate (Slightly). Methanol (Slightly)
• Appearance: Off-White Solid
• Storage: -20°C, Hygroscopic
• IUPAC Name: [(3R,3aS,6R,6aS)-6-nitrooxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-yl] nitrate
• InChI: InChI=1S/C6H8N2O8/c9-7(10)15-3-1-13-6-4(16-8(11)12)2-14-5(3)6/h3-6H,1-2H2/t3-,4-,5-,6-/m1/s1
• InChIKey: MOYKHGMNXAOIAT-KVTDHHQDSA-N
• SMILES: C1C(C2C(O1)C(CO2)O[N+](=O)[O-])O[N+](=O)[O-]

Isomannide Dinitrate (Cat No.:C000694) is an organic nitrate compound used as a vasodilator and medication to alleviate chest pain (angina) and manage heart conditions. It works by relaxing blood vessels, improving blood flow, and reducing the heart’s workload. Isomannide Dinitrate is metabolized to release nitric oxide, a molecule that dilates blood vessels.

Reference

Rosseel, M. T., et al.: Biochem. Pharmacol., 22, 67 (1973); Halliday, J. E., et al.: J. Pharm. Pharmacol., 17, 309 (1965); Bogaert, M. G., et al.: Naunyn-Schmiedeberg’s Archives of Pharmacology, 275, 339 (1972)