Isomitraphylline

• CAT Number: I029576
• CAS Number: 4963-01-3
• Molecular Formula: C21H24N2O4
• Molecular Weight: 368.43
• Purity: 98%
• Synonyms: Isomitraphylline; Ajmalicine oxindole A
• Target: Disease Research Fields
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: methyl (1S,4aS,5aS,6S,10aR)-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate
• InChI: InChI=1S/C21H24N2O4/c1-12-14-10-23-8-7-21(16-5-3-4-6-17(16)22-20(21)25)18(23)9-13(14)15(11-27-12)19(24)26-2/h3-6,11-14,18H,7-10H2,1-2H3,(H,22,25)/t12-,13-,14+,18-,21-/m0/s1
• InChIKey: JMIAZDVHNCCPDM-NWQITLLVSA-N
• SMILES: C[C@H]1[C@H]2CN3CC[C@@]4([C@@H]3C[C@@H]2C(=CO1)C(=O)OC)C5=CC=CC=C5NC4=O

Isomitraphylline(CAT: I029576) is an oxindole alkaloid derived from plants in the Mitragyna genus, such as Mitragyna speciosa (kratom). It has been studied for its potential immunomodulatory and anti-inflammatory properties, as well as its role in modulating cellular signaling pathways. Isomitraphylline is particularly significant in pharmacological and natural product research, where it aids in exploring therapeutic applications for autoimmune diseases, inflammation, and related conditions. Its unique bioactive profile makes it a promising candidate for further investigation into plant-derived compounds and their mechanisms of action in health and disease.