For research use only. Not for therapeutic Use.
Isoprinosine (CAS 36703-88-5) is a complex of acetaminobenzoic acid, dimethylaminoisopropanol, and inosine in a 3:3:1 ratio. It has a number of immunomodulatory effects, including inducing T-lymphocyte differentiation, augmenting macrophage and NK cell functions, and stimulating IL-2 production.<br />
Isoprinosine also restores depressed immune responses in cancer patients after irradiation and reduces the incidence of infection in leukemia patients undergoing chemotherapy.
| Catalog Number | R058319 |
| CAS Number | 36703-88-5 |
| Synonyms | Inosine 1-(Dimethylamino)-2-propanol 4-(Acetylamino)benzoate; Aviral; Delimmun; Groprinosin; Imunovir; Imunoviral; Inosine Acedobene Dimepranol; Inosine Pranobex; Inosiplex; Isoprinosin; Isoprinosina; Isoviral; Methisoprinol; Metyzoprynol; Modimmunal |
| Molecular Formula | C52H78N10O17 |
| Purity | ≥95% |
| Solubility | Soluble in DMSO |
| Storage | Store at -20°C |
| IUPAC Name | 4-acetamidobenzoic acid;9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one;1-(dimethylamino)propan-2-ol |
| InChI | InChI=1S/C10H12N4O5.3C9H9NO3.3C5H13NO/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18;3*1-6(11)10-8-4-2-7(3-5-8)9(12)13;3*1-5(7)4-6(2)3/h2-4,6-7,10,15-17H,1H2,(H,11,12,18);3*2-5H,1H3,(H,10,11)(H,12,13);3*5,7H,4H2,1-3H3/t4-,6-,7-,10-;;;;;;/m1....../s1 |
| InChIKey | YLDCUKJMEKGGFI-QCSRICIXSA-N |
| SMILES | CC(CN(C)C)O.CC(CN(C)C)O.CC(CN(C)C)O.CC(=O)NC1=CC=C(C=C1)C(=O)O.CC(=O)NC1=CC=C(C=C1)C(=O)O.CC(=O)NC1=CC=C(C=C1)C(=O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)CO)O)O |
| Reference | 1: Glasky AJ, Gordon JF. Isoprinosine (inosine pranobex BAN, INPX) in the treatment of AIDS and other acquired immunodeficiencies of clinical importance. Cancer Detect Prev Suppl. 1987;1:597-609. Review. PubMed PMID: 2446760.<br /> |
