Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate

For research use only. Not for therapeutic Use.

  • CAT Number: I043295
  • CAS Number: 1337529-56-2
  • Molecular Formula: C18H17F5NO5P
  • Molecular Weight: 453.30
  • Purity: ≥95%
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Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate can be used to synthesis Sofosbuvir (HY-15005) to avoid the production of sofibuvir degradation impurities[1].


Catalog Number I043295
CAS Number 1337529-56-2
Synonyms

propan-2-yl (2S)-2-[[(2,3,4,5,6-pentafluorophenoxy)-phenoxyphosphoryl]amino]propanoate

Molecular Formula C18H17F5NO5P
Purity ≥95%
InChI InChI=1S/C18H17F5NO5P/c1-9(2)27-18(25)10(3)24-30(26,28-11-7-5-4-6-8-11)29-17-15(22)13(20)12(19)14(21)16(17)23/h4-10H,1-3H3,(H,24,26)/t10-,30+/m0/s1
InChIKey MIILDBHEJQLACD-PAUNIHGJSA-N
SMILES CC(C)OC(=O)C(C)NP(=O)(OC1=CC=CC=C1)OC2=C(C(=C(C(=C2F)F)F)F)F
Reference

[1]. Shi GH, et al. The preparation of Suo Feibuwei. CN109535213A.

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