For research use only. Not for therapeutic Use.
Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate can be used to synthesis Sofosbuvir (HY-15005) to avoid the production of sofibuvir degradation impurities[1].
Catalog Number | I043295 |
CAS Number | 1337529-56-2 |
Synonyms | propan-2-yl (2S)-2-[[(2,3,4,5,6-pentafluorophenoxy)-phenoxyphosphoryl]amino]propanoate |
Molecular Formula | C18H17F5NO5P |
Purity | ≥95% |
InChI | InChI=1S/C18H17F5NO5P/c1-9(2)27-18(25)10(3)24-30(26,28-11-7-5-4-6-8-11)29-17-15(22)13(20)12(19)14(21)16(17)23/h4-10H,1-3H3,(H,24,26)/t10-,30+/m0/s1 |
InChIKey | MIILDBHEJQLACD-PAUNIHGJSA-N |
SMILES | CC(C)OC(=O)C(C)NP(=O)(OC1=CC=CC=C1)OC2=C(C(=C(C(=C2F)F)F)F)F |
Reference | [1]. Shi GH, et al. The preparation of Suo Feibuwei. CN109535213A. |