Isopropyl ß-D-Thiogalactopyranoside, Dioxane Free

• CAT Number: R000145
• CAS Number: 367-93-1
• Molecular Formula: C9H18O5S
• Molecular Weight: 238.3
• Purity: ≥95%
• Synonyms: IPTG
• Storage: -20°C
• InChIKey: BPHPUYQFMNQIOC-NXRLNHOXSA-N

IPTG is a compound that induces transcription of the lac operon by  mimicking allolactose, a lactose metabolite. IPTG is routinely used as a tool in cloning and gene recombination to confirm successful gene insertion. IPTG induces the lac operon by binding to and releasing the lac repressor allowing transcription of lac genes including beta-galactosidase.

Reference

Chang, Lewis M., and N. C. Horton. /Crystal Structure of the Lactose Operon Repressor and Its Complexes with DNA and Inducer./ Europe PubMed Central 271.5253 (1996): 1247-254. Europepmc.org. Web. 4 Dec. 2012.