For research use only. Not for therapeutic Use.
Isosulfan Blue(Cat No.:M015871) is a synthetic dye used primarily in medical diagnostics, particularly in lymphography and sentinel lymph node mapping in patients with breast cancer and other malignancies. This blue dye helps surgeons identify and map lymph nodes during procedures, facilitating the removal of nodes likely to contain metastases. Upon injection, Isosulfan Blue binds to plasma proteins and is selectively taken up by the lymphatic system, allowing for visual tracking of lymph flow. Its use assists in the accurate staging of cancer and helps in making decisions regarding the extent of surgery needed.
Catalog Number | M015871 |
CAS Number | 68238-36-8 |
Synonyms | PATENT BLUE VIOLET F & D VERSION;PATENT BLUE V (V F) (C.I. no 42045 );Ethanaminium, N-4-4-(diethylamino)phenyl(2,5-disulfophenyl)methylene-2,5-cyclohexadien-1-ylidene-N-ethyl-, inner salt, sodium salt;Lymphazurin;N-[4-[[4-(Diethylamino)phenyl](2-sulf |
Molecular Formula | C27H31N2NaO6S2 |
Purity | ≥95% |
Storage | -20°C |
IUPAC Name | sodium;2-[[4-(diethylamino)phenyl]-(4-diethylazaniumylidenecyclohexa-2,5-dien-1-ylidene)methyl]benzene-1,4-disulfonate |
InChI | InChI=1S/C27H32N2O6S2.Na/c1-5-28(6-2)22-13-9-20(10-14-22)27(21-11-15-23(16-12-21)29(7-3)8-4)25-19-24(36(30,31)32)17-18-26(25)37(33,34)35;/h9-19H,5-8H2,1-4H3,(H-,30,31,32,33,34,35);/q;+1/p-1 |
InChIKey | NLUFDZBOHMOBOE-UHFFFAOYSA-M |
SMILES | CCN(CC)C1=CC=C(C=C1)C(=C2C=CC(=[N+](CC)CC)C=C2)C3=C(C=CC(=C3)S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+] |
Reference | 1: Hassanein AH, Sacks JM, Cooney DS. Optimizing perioperative lymphatic-venous 2: Weixler B, Rickenbacher A, Raptis DA, Viehl CT, Guller U, Rueff J, Zettl A, 3: Weber JJ, Wong JH. Periareolar or Peritumoral Injection of Isosulfan Blue and <br> 5: İlem-Özdemir D, Yararbas U, Zengel B, Ertan G, Asikoglu M. Preparation of 6: Ortiz D, Alvikas J, Riker AI. A Case of Severe Anaphylactic Reaction Secondary 7: OʼReilly EA, Prichard RS, Al Azawi D, Aucharaz N, Kelly G, Evoy D, Geraghty J, |