Isovalerylcarnitine chloride

• CAT Number: R059933
• CAS Number: 139144-12-0
• Molecular Formula: C12H24ClNO4
• Molecular Weight: 281.78
• Purity: ≥95%
• Synonyms: [(2R)-3-carboxy-2-(3-methylbutanoyloxy)propyl]-trimethylazanium;chloride
• InChI: InChI=1S/C12H23NO4.ClH/c1-9(2)6-12(16)17-10(7-11(14)15)8-13(3,4)5;/h9-10H,6-8H2,1-5H3;1H/t10-;/m1./s1
• InChIKey: HWDFIOSIRGUUSM-HNCPQSOCSA-N
• SMILES: CC(C)CC(=O)OC(CC(=O)O)C[N+](C)(C)C.[Cl-]

Isovalerylcarnitine chloride, a product of the catabolism of L-leucine, is a potent activator of the Ca2+-dependent proteinase (calpain) of human neutrophils[1].

Reference

[1]. Pontremoli S, et al. Isovalerylcarnitine is a specific activator of calpain of human neutrophils. Biochem Biophys Res Commun. 1987 Nov 13;148(3):1189-95.
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