For research use only. Not for therapeutic Use.
Isoverticine, a bioactive isosteroidal alkaloid isolated from bulbus of Fritillaria pallidiflora, displays significant cytotoxicity[1].
Isoverticine displays cytotoxicity, with IC50s of 49.56, 31.63, 61.91 and 108.8 µg/mL, respectively[1].
Catalog Number | I044911 |
CAS Number | 23496-43-7 |
Synonyms | (1R,2S,6S,9S,10S,11S,14S,15S,17R,18S,20S,23R,24S)-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosane-10,17,20-triol |
Molecular Formula | C27H45NO3 |
Purity | ≥95% |
InChI | InChI=1S/C27H45NO3/c1-15-4-7-25-27(3,31)21-6-5-17-18(20(21)14-28(25)13-15)11-22-19(17)12-24(30)23-10-16(29)8-9-26(22,23)2/h15-25,29-31H,4-14H2,1-3H3/t15-,16-,17+,18+,19-,20-,21-,22-,23+,24+,25-,26+,27-/m0/s1 |
InChIKey | IUKLSMSEHKDIIP-RZNVUHDWSA-N |
SMILES | CC1CCC2C(C3CCC4C(C3CN2C1)CC5C4CC(C6C5(CCC(C6)O)C)O)(C)O |
Reference | [1]. Wang D, et al. Characterization of the Isosteroidal Alkaloid Chuanbeinone from Bulbus of Fritillaria pallidiflora as Novel Antitumor Agent In Vitro and In Vivo. Planta Med. 2016;82(3):195-204. |