For research use only. Not for therapeutic Use.
Isradipine is a calcium channel blocker used primarily in the treatment of hypertension (high blood pressure) and angina (chest pain). It works by inhibiting the influx of calcium ions into smooth muscle cells and cardiac cells, leading to vasodilation (widening of blood vessels) and a reduction in blood pressure. By relaxing blood vessels, isradipine helps to reduce the heart’s workload. It is typically prescribed when other medications are ineffective or not well-tolerated, and may also be used for migraine prevention.
| Catalog Number | A000767 |
| CAS Number | 75695-93-1 |
| Synonyms | 75695-93-1; DynaCirc; Isradipin; Lomir; Isrodipine |
| Molecular Formula | C19H21N3O5 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | >12.6mg/mL in DMSO |
| Storage | -20°C |
| IUPAC Name | 3-O-methyl 5-O-propan-2-yl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate |
| InChI | 1S/C19H21N3O5/c1-9(2)26-19(24)15-11(4)20-10(3)14(18(23)25-5)16(15)12-7-6-8-13-17(12)22-27-21-13/h6-9,16,20H,1-5H3 |
| InChIKey | HMJIYCCIJYRONP-UHFFFAOYSA-N |
| SMILES | CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC=CC3=NON=C32)C(=O)OC |
