Itraconazole

• CAT Number: A000258
• CAS Number: 84625-61-6
• Molecular Formula: C₃₅H₃₈Cl₂N₈O₄
• Molecular Weight: 705.63
• Purity: ≥95%
• Synonyms: 84625-61-6; Oriconazole; Sporanox; Itraconazolum [Latin]; ITRAZOLE
• Target: Antibiotic
• Solubility: >8.8mg/mL in DMSO
• Storage: -20°C
• InChI: InChI=1S/C35H38Cl2N8O4/c1-3-25(2)45-34(46)44(24-40-45)29-7-5-27(6-8-29)41-14-16-42(17-15-41)28-9-11-30(12-10-28)47-19-31-20-48-35(49-31,21-43-23-38-22-39-43)32-13-4-26(36)18-33(32)37/h4-13,18,22-25,31H,3,14-17,19-21H2,1-2H3/t25?,31-,35-/m1/s1
• InChIKey: VHVPQPYKVGDNFY-AVQIMAJZSA-N
• SMILES: CCC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5COC(O5)(CN6C=NC=N6)C7=C(C=C(C=C7)Cl)Cl

Itraconazole, invented in 1984, is a triazole antifungal agent prescribed to patients with fungal infections. It has also recently been explored as an anticancer agent for patients with basal cell carcinoma, non-small cell lung cancer, and prostate cancer. The drug may be given orally or intravenously.

Reference

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