IUN-36463

• CAT Number: I029670
• CAS Number: 2271036-46-3
• Molecular Formula: C21H26N6O7
• Molecular Weight: 474.474
• Purity: 98%
• Synonyms: IUN-36463; IUN36463; IUN 36463; Pomalidomide 4'-PEG3-azide
• Target: E3 Ligase Ligand-Linker Conjugates
• Solubility: To be determined
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 4-((2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
• InChI: InChI=1S/C21H26N6O7/c22-26-24-7-9-33-11-13-34-12-10-32-8-6-23-15-3-1-2-14-18(15)21(31)27(20(14)30)16-4-5-17(28)25-19(16)29/h1-3,16,23H,4-13H2,(H,25,28,29)
• InChIKey: IRPMZWZENVORCT-UHFFFAOYSA-N
• SMILES: [N-]=[N+]=NCCOCCOCCOCCNC1=C2C(N(C3CCC(NC3=O)=O)C(C2=CC=C1)=O)=O

IUN-36463 is a Functionalized cereblon ligand for PROTAC® research and development. It incorporates an E3 ligase ligand plus a PEG3 linker with terminal azide ready for conjugation to a target protein ligand. IUN-36463 is Part of a range of functionalized tool molecules for PROTAC R&D. This product has no formal name. For the convenience of scientific communication, we named it by combining its InChi Key (3 letters from the first letter of each section) with the last 5 digit of its CAS#) according to MedKoo Chemical Nomenclature (https://www.medkoo.com/page/naming).