For research use only. Not for therapeutic Use.
IUN-36463(CAT: I029670) is a functionalized cereblon (CRBN) ligand designed for use in PROTAC® (proteolysis-targeting chimera) research and development. By specifically binding to the CRBN E3 ubiquitin ligase, it facilitates targeted protein degradation when incorporated into PROTAC constructs. This compound is particularly valuable in the field of drug discovery, enabling the study and development of selective degraders for challenging protein targets. IUN-36463 provides researchers with a robust tool for exploring novel therapeutic strategies and advancing precision medicine through targeted protein degradation technologies.
| CAS Number | 2271036-46-3 |
| Synonyms | IUN-36463; IUN36463; IUN 36463; Pomalidomide 4'-PEG3-azide; |
| Molecular Formula | C21H26N6O7 |
| Purity | 98% |
| Target | E3 Ligase Ligand-Linker Conjugates |
| Solubility | To be determined |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 4-((2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione |
| InChI | InChI=1S/C21H26N6O7/c22-26-24-7-9-33-11-13-34-12-10-32-8-6-23-15-3-1-2-14-18(15)21(31)27(20(14)30)16-4-5-17(28)25-19(16)29/h1-3,16,23H,4-13H2,(H,25,28,29) |
| InChIKey | IRPMZWZENVORCT-UHFFFAOYSA-N |
| SMILES | [N-]=[N+]=NCCOCCOCCOCCNC1=C2C(N(C3CCC(NC3=O)=O)C(C2=CC=C1)=O)=O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
