For research use only. Not for therapeutic Use.
IUN76750 (Cat No.: I029672) is a selective and potent orexin receptor antagonist, designed to modulate the orexin signaling pathway involved in sleep-wake regulation. By blocking orexin receptors, particularly OX1R and OX2R, IUN76750 promotes sleep and shows potential as a therapeutic agent for insomnia and other sleep disorders. It demonstrates favorable pharmacokinetic properties, good brain penetration, and minimal off-target activity. IUN76750 is a valuable tool in neuroscience research for studying sleep mechanisms and exploring new treatments targeting the orexin system.
| CAS Number | 1690176-75-0 |
| Synonyms | IUN76750; IUN-76750; IUN 76750; |
| Molecular Formula | C12H14ClN3O2 |
| Purity | 98% |
| Target | Protease Activated Receptor (PAR) |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate |
| InChI | InChI=1S/C12H14ClN3O2/c1-12(2,3)7-5-9(13)15-16-6-8(11(17)18-4)14-10(7)16/h5-6H,1-4H3 |
| InChIKey | IUYKWCFRPDFUQU-UHFFFAOYSA-N |
| SMILES | O=C(C1=CN2N=C(Cl)C=C(C(C)(C)C)C2=N1)OC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
