For research use only. Not for therapeutic Use.
Ivabradine Hemisulfate(CAT: I029673) is a selective inhibitor of the cardiac pacemaker If current in the sinoatrial node, reducing heart rate without affecting myocardial contractility or blood pressure. This mechanism makes it particularly effective in the treatment of chronic stable angina and heart failure with reduced ejection fraction (HFrEF). By slowing heart rate, Ivabradine Hemisulfate improves myocardial oxygen supply and reduces cardiac workload. It is widely used in cardiovascular research to study heart rate modulation and its impact on cardiac function. Its specificity and favorable safety profile make it a valuable tool for advancing therapeutic strategies in heart-related disorders.
| CAS Number | 1422274-66-5 |
| Synonyms | Ivabradine hemisulfate |
| Molecular Formula | C54H74N4O14S |
| Purity | 98% |
| Solubility | To be determined |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 2H-3-Benzazepin-2-one, 3-(3-((((7S)-3,4-dimethoxybicyclo(4.2.0)octa-1,3,5-trien-7-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-, sulfate (2:1) |
| InChI | InChI=1S/2C27H36N2O5.H2O4S/c2*1-28(17-21-11-20-14-25(33-4)26(34-5)16-22(20)21)8-6-9-29-10-7-18-12-23(31-2)24(32-3)13-19(18)15-27(29)30;1-5(2,3)4/h2*12-14,16,21H,6-11,15,17H2,1-5H3;(H2,1,2,3,4)/t2*21-;/m11./s1 |
| InChIKey | AMRKLKWJQKOGOF-ITEXDBGESA-N |
| SMILES | CN(CCCN1CCC2=CC(=C(C=C2CC1=O)OC)OC)C[C@H]3CC4=CC(=C(C=C34)OC)OC.CN(CCCN1CCC2=CC(=C(C=C2CC1=O)OC)OC)C[C@H]3CC4=CC(=C(C=C34)OC)OC.OS(=O)(=O)O |
