Ivabradine impurity 1

• CAT Number: I014442
• CAS Number: 1428869-91-3
• Molecular Formula: C₁₅H₁₈BrNO₃
• Molecular Weight: 340.21
• Purity: ≥95%
• Target: Drug Metabolite
• IUPAC Name: 3-(3-bromopropyl)-7,8-dimethoxy-1H-3-benzazepin-2-one
• InChI: InChI=1S/C15H18BrNO3/c1-19-13-8-11-4-7-17(6-3-5-16)15(18)10-12(11)9-14(13)20-2/h4,7-9H,3,5-6,10H2,1-2H3
• InChIKey: VFTMJYBDEYQZHG-UHFFFAOYSA-N
• SMILES: COC1=C(C=C2C=CN(C(=O)CC2=C1)CCCBr)OC

Ivabradine Impurity 1(CAT: I014442) is a chemical byproduct or degradation product that can be formed during the synthesis or storage of Ivabradine, a medication primarily used to treat certain heart conditions such as chronic heart failure and angina. Impurities like Ivabradine Impurity 1 are closely monitored and characterized in pharmaceutical research and production to ensure the safety, efficacy, and quality of the drug. The presence of such impurities needs to be controlled within acceptable limits as defined by regulatory authorities. Identifying and studying Ivabradine Impurity 1 is crucial for understanding the drug’s stability, optimizing manufacturing processes, and ensuring that the final product meets rigorous pharmaceutical standards.

Reference

[1]. Fang, Y., et al. Heart rate reduction induced by the if current inhibitor ivabradine improves diastolic function and attenuates cardiac tissue hypoxia. J Cardiovasc Pharmacol, 2012. 59(3): p. 260-7.