For research use only. Not for therapeutic Use.
J14 (CAT: I017539) is a reversible sulfiredoxin inhibitor. Sulfiredoxin is an enzyme involved in the regulation of cellular redox balance by catalyzing the reduction of hyperoxidized peroxiredoxins. By inhibiting sulfiredoxin, J14 disrupts the cellular redox signaling pathway, leading to altered cellular responses and potential therapeutic effects. J14 has been investigated for its role in oxidative stress-related diseases and as a tool compound for studying redox signaling pathways.
| Catalog Number | I017539 |
| CAS Number | 1043854-13-2 |
| Molecular Formula | C₂₈H₂₅ClN₄O₂S |
| Purity | ≥95% |
| Target | NF-κB |
| Reference | [1]. Kim H, et al. Sulfiredoxin inhibitor induces preferential death of cancer cells through reactive oxygen species-mediated mitochondrial damage. Free Radic Biol Med. 2016 Feb;91:264-74. |
