For research use only. Not for therapeutic Use.
JAB-3068 (SHP2-IN-6) is a potent allosteric inhibitor of SHP2. JAB-3068 enhances the anti-tumor activity of CD8+ T cells and can be used in combination to address non-responsive tumors alongside PD-1/PD-L1 antibodies.
| Catalog Number | I015145 |
| CAS Number | 2169223-48-5 |
| Molecular Formula | C22H26F2N6O2S |
| Purity | ≥95% |
| Reference | [1] Liu M, et al. Acta Pharm Sin B. 2021 Dec;11(12):3908-3924. |
