For research use only. Not for therapeutic Use.
JAK-IN-25（Cat No.:I041158）is a potent and selective inhibitor of Janus kinase (JAK) enzymes, which play a critical role in cytokine signaling and the regulation of immune responses. By inhibiting JAK1, JAK2, and JAK3, JAK-IN-25 blocks downstream signaling pathways involved in inflammation, cell proliferation, and immune cell activation. This compound is being investigated for its therapeutic potential in autoimmune diseases, inflammatory disorders, and certain cancers, where dysregulated JAK activity contributes to disease pathogenesis. JAK-IN-25 offers a promising approach for targeted treatment of diseases linked to aberrant JAK-mediated signaling.
| CAS Number | 2127110-22-7 |
| Synonyms | methyl 6-[1-[(4-methoxyphenyl)methyl]pyrazol-4-yl]-4-oxo-5H-pyrazolo[1,5-a]pyrazine-2-carboxylate |
| Molecular Formula | C19H17N5O4 |
| Purity | ≥95% |
| IUPAC Name | methyl 6-[1-[(4-methoxyphenyl)methyl]pyrazol-4-yl]-4-oxo-5H-pyrazolo[1,5-a]pyrazine-2-carboxylate |
| InChI | InChI=1S/C19H17N5O4/c1-27-14-5-3-12(4-6-14)9-23-10-13(8-20-23)16-11-24-17(18(25)21-16)7-15(22-24)19(26)28-2/h3-8,10-11H,9H2,1-2H3,(H,21,25) |
| InChIKey | KJSUDTXSTRQSEJ-UHFFFAOYSA-N |
| SMILES | COC1=CC=C(C=C1)CN2C=C(C=N2)C3=CN4C(=CC(=N4)C(=O)OC)C(=O)N3 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
