For research use only. Not for therapeutic Use.
JAMM protein inhibitor 2 (compound 180) is a potent JAMM protease inhibitor with IC50s of 10 μM, 46 μM and 89 μM for thrombin, Rpn11 and MMP2, respectively. JAMM protein inhibitor 2 can be used for researching anticancer[1]
| Catalog Number | I043536 |
| CAS Number | 848249-35-4 |
| Synonyms | 2-(2-ethylphenoxy)-N-(2-methyl-4-pyrrolidin-1-ylphenyl)acetamide |
| Molecular Formula | C21H26N2O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C21H26N2O2/c1-3-17-8-4-5-9-20(17)25-15-21(24)22-19-11-10-18(14-16(19)2)23-12-6-7-13-23/h4-5,8-11,14H,3,6-7,12-13,15H2,1-2H3,(H,22,24) |
| InChIKey | BWVQJXWDZCDJJJ-UHFFFAOYSA-N |
| SMILES | CCC1=CC=CC=C1OCC(=O)NC2=C(C=C(C=C2)N3CCCC3)C |
| Reference | [1]. Han-Jie Zhou, et al. Methods and compositions for jamm protease inhibition. WO2013123071A1 (compound 180) |
