Jaspamycin

• CAT Number: I019392
• CAS Number: 22242-96-2
• Molecular Formula: C₁₂H₁₂N₄O₅
• Molecular Weight: 292.25
• Purity: ≥95%
• Target: TGF-beta/Smad
• Storage: Store at -20°C
• IUPAC Name: 7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-oxo-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
• InChI: InChI=1S/C12H12N4O5/c13-1-5-2-16(10-7(5)11(20)15-4-14-10)12-9(19)8(18)6(3-17)21-12/h2,4,6,8-9,12,17-19H,3H2,(H,14,15,20)/t6-,8-,9-,12-/m1/s1
• InChIKey: SKDKFLFSBDYEDO-WOUKDFQISA-N
• SMILES: C1=C(C2=C(N1C3C(C(C(O3)CO)O)O)N=CNC2=O)C#N

Jaspamycin (also known as Toyocamycin) is a natural nucleoside antibiotic derived from Streptomyces species. It exhibits potent antimicrobial, antiviral, and anticancer activities by inhibiting RNA synthesis through incorporation into RNA molecules, disrupting proper transcription processes. Jaspamycin has shown efficacy in research targeting viral infections and specific cancers, making it a valuable tool for studying nucleoside analogs and their therapeutic potential. Its unique mechanism of action highlights its importance in advancing research in infectious diseases and oncology.