JC124

• CAT Number: I029753
• CAS Number: 1638611-48-9
• Molecular Formula: C17H19ClN2O4S
• Molecular Weight: 382.86
• Purity: 98%
• Synonyms: JC124; JC-124; JC 124
• Target: NOD-like Receptor (NLR)
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 5-chloro-2-methoxy-N-[2-[4-(methylsulfamoyl)phenyl]ethyl]benzamide
• InChI: InChI=1S/C17H19ClN2O4S/c1-19-25(22,23)14-6-3-12(4-7-14)9-10-20-17(21)15-11-13(18)5-8-16(15)24-2/h3-8,11,19H,9-10H2,1-2H3,(H,20,21)
• InChIKey: LXYPQRJNQPYTQW-UHFFFAOYSA-N
• SMILES: CNS(=O)(=O)C1=CC=C(C=C1)CCNC(=O)C2=C(C=CC(=C2)Cl)OC

JC124（Cat No.:I029753）is a synthetic compound that acts as a selective antagonist of the 5-HT3 receptor, a serotonin receptor subtype involved in regulating neurotransmission in the brain and gastrointestinal tract. By blocking these receptors, JC124 has potential therapeutic applications in treating conditions like nausea, vomiting, and gastrointestinal disorders, as well as certain psychiatric conditions like anxiety and depression. Preclinical studies suggest that JC124 could offer a new approach to managing serotonin-related imbalances without the side effects typically associated with other 5-HT3 receptor antagonists. Further clinical research is needed to confirm its efficacy and safety.