JNJ 10397049

• CAT Number: R015878
• CAS Number: 708275-58-5
• Molecular Formula: C19H20Br2N2O3
• Molecular Weight: 484.188
• Purity: ≥95%
• Synonyms: N-(2,4-Dibromophenyl)-N’-[(4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl]-urea; 1-(2,4-Dibromophenyl)-3-((4S,5S)-2,2-dimethyl-4-phenyl-[1,3]dioxan-5-yl)urea
• Target: Neuronal Signaling
• Solubility: Soluble in DMSO > 10 mM
• Storage: Store at +4C
• IUPAC Name: 1-(2,4-dibromophenyl)-3-[(4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl]urea
• InChI: InChI=1S/C19H20Br2N2O3/c1-19(2)25-11-16(17(26-19)12-6-4-3-5-7-12)23-18(24)22-15-9-8-13(20)10-14(15)21/h3-10,16-17H,11H2,1-2H3,(H2,22,23,24)/t16-,17-/m0/s1
• InChIKey: RBKIJGLHFFQHBE-IRXDYDNUSA-N
• SMILES: CC1(OCC(C(O1)C2=CC=CC=C2)NC(=O)NC3=C(C=C(C=C3)Br)Br)C

JNJ 10397049 (Cat. No: R015878) is an efficient and selective inhibitor of the orexin 2 receptor. Its activity to the OX2 receptor is much higher than that to the OX1 receptor. This product is mainly used for preclinical and scientific research.

Reference

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