JNJ-678

• CAT Number: I020081
• CAS Number: 1383450-81-4
• Molecular Formula: C₂₁H₂₀ClF₃N₄O₃S
• Molecular Weight: 500.92
• Purity: ≥95%
• Target: RSV
• Storage: Store at -20°C
• IUPAC Name: 3-[[5-chloro-1-(3-methylsulfonylpropyl)indol-2-yl]methyl]-1-(2,2,2-trifluoroethyl)imidazo[4,5-c]pyridin-2-one
• InChI: InChI=1S/C21H20ClF3N4O3S/c1-33(31,32)8-2-7-27-16(10-14-9-15(22)3-4-17(14)27)12-28-19-11-26-6-5-18(19)29(20(28)30)13-21(23,24)25/h3-6,9-11H,2,7-8,12-13H2,1H3
• InChIKey: GTQTUABHRCWVLL-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)CCCN1C2=C(C=C(C=C2)Cl)C=C1CN3C4=C(C=CN=C4)N(C3=O)CC(F)(F)F

JNJ-678（Cat No.:I020081）is a potent and selective small-molecule inhibitor widely used in oncology and immunology research. It targets specific signaling pathways involved in tumor growth and immune modulation, offering insights into disease mechanisms and therapeutic potential. JNJ-678 demonstrates high specificity and favorable pharmacokinetic properties, making it ideal for preclinical studies and drug discovery. This compound is particularly valuable for exploring targeted therapies, resistance mechanisms, and combination treatment strategies. Researchers rely on JNJ-678 to advance the understanding of complex cellular pathways and develop innovative approaches to disease treatment.

Reference

[1]. Roymans D, et al. Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor. Nat Commun. 2017 Aug 1;8(1):167.