For research use only. Not for therapeutic Use.
JNK-IN-13(cat: I040665) is a selective inhibitor of c-Jun N-terminal kinase (JNK), a key member of the MAPK family involved in regulating cellular responses to stress, inflammation, and apoptosis. By blocking JNK activity, JNK-IN-13 modulates downstream signaling pathways such as AP-1 transcription, offering therapeutic potential in conditions like cancer, neurodegeneration, metabolic disorders, and inflammatory diseases. This compound is widely used in cellular and in vivo studies to dissect JNK-mediated pathways and validate JNK as a drug target. With high potency and selectivity, JNK-IN-13 is an essential tool for advancing research in stress-related and proliferative disease mechanisms.
| CAS Number | 345986-38-1 |
| Synonyms | 2-(1,3-benzothiazol-2-yl)-2-(2-chloropyrimidin-4-yl)acetonitrile |
| Molecular Formula | C13H7ClN4S |
| Purity | ≥95% |
| IUPAC Name | 2-(1,3-benzothiazol-2-yl)-2-(2-chloropyrimidin-4-yl)acetonitrile |
| InChI | InChI=1S/C13H7ClN4S/c14-13-16-6-5-9(18-13)8(7-15)12-17-10-3-1-2-4-11(10)19-12/h1-6,8H |
| InChIKey | QVMKLKBODZHJDK-UHFFFAOYSA-N |
| SMILES | C1=CC=C2C(=C1)N=C(S2)C(C#N)C3=NC(=NC=C3)Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
