For research use only. Not for therapeutic Use.
JNK-IN-13 (compound 1) is a potent and selective JNK inhibitor with IC50s of 290 nM and 500 nM for JNK3 and JNK2, respectively[1].
| Catalog Number | I040665 |
| CAS Number | 345986-38-1 |
| Synonyms | 2-(1,3-benzothiazol-2-yl)-2-(2-chloropyrimidin-4-yl)acetonitrile |
| Molecular Formula | C13H7ClN4S |
| Purity | ≥95% |
| InChI | InChI=1S/C13H7ClN4S/c14-13-16-6-5-9(18-13)8(7-15)12-17-10-3-1-2-4-11(10)19-12/h1-6,8H |
| InChIKey | QVMKLKBODZHJDK-UHFFFAOYSA-N |
| SMILES | C1=CC=C2C(=C1)N=C(S2)C(C#N)C3=NC(=NC=C3)Cl |
| Reference | [1]. Serge Halazy, et al. Benzazole derivatives and their use as JNK modulators. EP1110957A1. |
