(+)-JQ1 PA

• CAT Number: I019806
• CAS Number: 2115701-93-2
• Molecular Formula: C₂₂H₂₀ClN₅OS
• Molecular Weight: 437.95
• Purity: ≥95%
• Target: Epigenetic Reader Domain

(+)-JQ1 PA (Cat.No:I019806) is a potent and selective bromodomain and extraterminal domain (BET) inhibitor. It acts by disrupting the binding of BET proteins to acetylated histones, leading to the suppression of gene transcription. (+)-JQ1 PA has shown promising anti-cancer activity in preclinical studies, making it a potential candidate for cancer therapy.

Reference

[1]. Tyler DS, et al. Click chemistry enables preclinical evaluation of targeted epigenetic therapies. Science. 2017 Jun 30;356(6345):1397-1401.