Juvenile Hormone III

• CAT Number: M006609
• CAS Number: 22963-93-5
• Molecular Formula: C16H26O3
• Molecular Weight: 266.381
• Purity: ≥95%
• Synonyms: TRANS,TRANS-10,11-EPOXY-3,7,11-TRIMETHYL-2,6-DODECADIENIC ACID METHYL ESTER;10-EPOXY-3,7,11-TRIMETHYL-TRANS,TRANS-2,6-DODECADIENOIC ACID METHYL ESTER;MANDUCA HORMONE;JH-III;JH II;JUVENILE HORMONE 11;JUVENILE HORMONE III;[+/-]-CIS-10,11-EPOXY-3,7,11-T
• Storage: -20°C
• IUPAC Name: methyl (2E,6E)-9-[(2R)-3,3-dimethyloxiran-2-yl]-3,7-dimethylnona-2,6-dienoate
• InChI: InChI=1S/C16H26O3/c1-12(9-10-14-16(3,4)19-14)7-6-8-13(2)11-15(17)18-5/h7,11,14H,6,8-10H2,1-5H3/b12-7+,13-11+/t14-/m1/s1
• InChIKey: QVJMXSGZTCGLHZ-HONBPKQLSA-N
• SMILES: CC(=CCCC(=CC(=O)OC)C)CCC1C(O1)(C)C

Juvenile Hormone III (CAS 22963-93-5) is an acyclic sesquiterpenoid that regulates diverse processes in insects, including adult transition of larvae and oogenesis in adult females. It activates the juvenile hormone receptor, known as methoprene-tolerant, with a Kd value of 2.9 nM. Juvenile hormone III can be synthesized from farnesoic acid by two alternative pathways, one through methyl farnesoate and the other through juvenile hormone acid III.