For research use only. Not for therapeutic Use.
JW480 is a potent and selective inhibitor of a serine hydrolase enzyme KIAA1363[1].
Catalog Number | I010934 |
CAS Number | 1354359-53-7 |
Synonyms | (2-propan-2-ylphenyl) N-(2-naphthalen-2-ylethyl)carbamate |
Molecular Formula | C22H23NO2 |
Purity | ≥95% |
InChI | InChI=1S/C22H23NO2/c1-16(2)20-9-5-6-10-21(20)25-22(24)23-14-13-17-11-12-18-7-3-4-8-19(18)15-17/h3-12,15-16H,13-14H2,1-2H3,(H,23,24) |
InChIKey | PCNJGBMWAZRVEA-UHFFFAOYSA-N |
SMILES | CC(C)C1=CC=CC=C1OC(=O)NCCC2=CC3=CC=CC=C3C=C2 |
Reference | [1]. Chang JW, et al. A potent and selective inhibitor of KIAA1363/AADACL1 that impairs prostate cancer pathogenesis. Chem Biol. 2011 Apr 22;18(4):476-84. |