For research use only. Not for therapeutic Use.
JWH 018 (R064965) is a mildly selective agonist of the peripheral cannabinoid (CB2) receptor with Ki values of 9.0 and 2.94 nM for the central cannabinoid (CB1) and CB2 receptors, respectively. JWH 018 benzimidazole analog replaces the indole core of JWH 018 with a benzimidazole core. While the physiological and toxicological properties of this compound have not been tested, other benzimidazole derivatives demonstrate high selectivity for the CB2 receptor. This product is intended for forensic and research applications.
| Catalog Number | R064965 |
| Synonyms | BIM-018 |
| Molecular Formula | C23H22N2O |
| Purity | ≥95% |
| Storage | -20°C |
| InChI | InChI=1S/C23H22N2O/c1-2-3-8-16-25-21-15-7-6-14-20(21)24-23(25)22(26)19-13-9-11-17-10-4-5-12-18(17)19/h4-7,9-15H,2-3,8,16H2,1H3 |
| InChIKey | ZJWSSWFQIOEVCU-UHFFFAOYSA-N |
| SMILES | O=C(C1=C(C=CC=C2)C2=CC=C1)C3=NC4=C(C=CC=C4)N3CCCCC |
| Reference | 1.Aung, M.M.,Griffin, G.,Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug and Alcohol Dependence 60, 133-140 (2000). |
