For research use only. Not for therapeutic Use.
JWH 019 (Item No. <span class=/itemid/>13633</span>) is a cannabimimetic indole that shows a high-<wbr></wbr>affinity for both the central cannabinoid (CB<sub>1</sub>) (K<sub>i</sub> = 9.8 nM) and the peripheral cannabinoid (CB<sub>2</sub>) (K<sub>i</sub> = 5.6 nM) receptors. JWH 019 N-<wbr></wbr>(6-<wbr></wbr>hydroxyhexyl) β-<wbr></wbr>D-<wbr></wbr>Glucuronide is an expected major urinary metabolite of JWH 019, based on the metabolism of similar cannabimimetics. The physiological and toxicological properties of this compound have not been tested. This product is intended for forensic and research applications.
| Catalog Number | R059129 |
| CAS Number | 1630023-00-5 |
| Synonyms | (2S,3S,4S,5R,6R)-6-((6-(3-(1-naphthoyl)-1H-indol-1-yl)hexyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid |
| Molecular Formula | C31H33NO8 |
| Purity | ≥95% |
| Storage | -20°C |
| InChI | InChI=1S/C31H33NO8/c33-25(22-14-9-11-19-10-3-4-12-20(19)22)23-18-32(24-15-6-5-13-21(23)24)16-7-1-2-8-17-39-31-28(36)26(34)27(35)29(40-31)30(37)38/h3-6,9-15,18,26-29,31,34-36H,1-2,7-8,16-17H2,(H,37,38)/t26-,27-,28+,29?,31+/m0/s1 |
| InChIKey | AWPUOPYMUOPGIN-NXRHVYQJSA-N |
| SMILES | O=C(C1=CN(CCCCCCO[C@@H]2O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]2O)C3=C1C=CC=C3)C4=C5C(C=CC=C5)=CC=C4 |
| Reference | 1.Aung, M.M.,Griffin, G.,Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug and Alcohol Dependence 60, 133-140 (2000). |
