For research use only. Not for therapeutic Use.
JWH 073 is a synthetic cannabinoid (CB) that activates both the central cannabinoid (CB<sub>1</sub>) and the peripheral cannabinoid (CB<sub>2</sub>) receptors (K<sub>i</sub> = 8.9 and 38 nM, respectively). This cannabimimetic compound has been identified in herbal blends. JWH 073 2’-<wbr></wbr>naphthyl-<wbr></wbr>N-<wbr></wbr>(1,1-<wbr></wbr>dimethylethyl) isomer differs structurally from JWH 073 by having the naphthyl group attached at the 2 position and a 1,1-<wbr></wbr>dimethylethyl group in place of a butyl chain. The biological and toxicological properties of this compound have not been characterized. This product is intended for forensic and research applications.
| Catalog Number | R067473 |
| Synonyms | (1-(tert-butyl)-1H-indol-3-yl)(naphthalen-2-yl)methanone |
| Molecular Formula | C23H21NO |
| Purity | ≥95% |
| Storage | -20°C |
| InChI | InChI=1S/C23H21NO/c1-23(2,3)24-15-20(19-10-6-7-11-21(19)24)22(25)18-13-12-16-8-4-5-9-17(16)14-18/h4-15H,1-3H3 |
| InChIKey | WXDJZVMXYNCQLO-UHFFFAOYSA-N |
| SMILES | O=C(C1=CN(C(C)(C)C)C2=C1C=CC=C2)C3=CC4=C(C=CC=C4)C=C3 |
| Reference | 1.Aung, M.M.,Griffin, G.,Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug and Alcohol Dependence 60, 133-140 (2000). |
