For research use only. Not for therapeutic Use.
JWH 073 is a synthetic cannabinoid (CB) that activates both the central CB<sub>1</sub> and peripheral CB<sub>2</sub> receptors (K<sub>i</sub> = 8.9 and 38 nM, respectively). This cannabimimetic compound has been found in herbal blends. JWH 073 N-<wbr></wbr>(2-<wbr></wbr>methylpropyl) isomer differs structurally from JWH 073 by having a methylpropyl group, rather than a butyl chain, extending from the indole group. The biological activities of this compound have not been characterized.
| Catalog Number | R067467 |
| CAS Number | 1528793-12-5 |
| Synonyms | (1-isobutyl-1H-indol-3-yl)(naphthalen-1-yl)methanone |
| Molecular Formula | C23H21NO |
| Purity | ≥95% |
| Storage | -20°C |
| InChI | InChI=1S/C23H21NO/c1-16(2)14-24-15-21(19-11-5-6-13-22(19)24)23(25)20-12-7-9-17-8-3-4-10-18(17)20/h3-13,15-16H,14H2,1-2H3 |
| InChIKey | XNFHBVYEKFAQLX-UHFFFAOYSA-N |
| SMILES | O=C(C1=CC=CC2=C1C=CC=C2)C3=CN(CC(C)C)C4=CC=CC=C43 |
| Reference | 1.Aung, M.M.,Griffin, G.,Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug and Alcohol Dependence 60, 133-140 (2000). |
