For research use only. Not for therapeutic Use.
JWH 182 is a potent synthetic cannabinoid (CB), activating the central CB<sub>1</sub> receptor with a K<sub>i</sub> value of 0.65 nM and the peripheral CB<sub>2</sub> receptor with a K<sub>i</sub> value of 1.1 nM. Its effects in cells and animals are unknown.
| Catalog Number | R048051 |
| CAS Number | 824960-02-3 |
| Synonyms | (1-pentyl-1H-indol-3-yl)(4-propyl-1-naphthalenyl)-methanone |
| Molecular Formula | C27H29NO |
| Purity | ≥95% |
| IUPAC Name | (1-pentylindol-3-yl)-(4-propylnaphthalen-1-yl)methanone |
| InChI | InChI=1S/C27H29NO/c1-3-5-10-18-28-19-25(23-14-8-9-15-26(23)28)27(29)24-17-16-20(11-4-2)21-12-6-7-13-22(21)24/h6-9,12-17,19H,3-5,10-11,18H2,1-2H3 |
| InChIKey | AKGUMDFQXWZHHS-UHFFFAOYSA-N |
| SMILES | CCCCCN1C=C(C2=CC=CC=C21)C(=O)C3=CC=C(C4=CC=CC=C43)CCC |
| Reference | 1.Huffman, J.W.,Zengin, G.,Wu, M.J., et al. Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB1 and CB2 receptors: steric and electronic effects of naphthoyl substituents. New highly selective CB2 receptor agonists. |
