JWH 250-d5

• CAT Number: R048395
• CAS Number: 1651833-53-2
• Molecular Formula: C22H20D5NO2
• Molecular Weight: 340.5
• Purity: ≥95%
• Synonyms: 1-(1-pentyl-1H-indol-3-yl)-2-(2-methoxyphenyl)-ethanone-2,4,5,6,7-d5
• Storage: -20°C
• IUPAC Name: 2-(2-methoxyphenyl)-1-(2,4,5,6,7-pentadeuterio-1-pentylindol-3-yl)ethanone
• InChI: InChI=1S/C22H25NO2/c1-3-4-9-14-23-16-19(18-11-6-7-12-20(18)23)21(24)15-17-10-5-8-13-22(17)25-2/h5-8,10-13,16H,3-4,9,14-15H2,1-2H3/i6D,7D,11D,12D,16D
• InChIKey: FFLSJIQJQKDDCM-JZDSKUDLSA-N
• SMILES: [2H]C1=C(C(=C2C(=C1[2H])C(=C(N2CCCCC)[2H])C(=O)CC3=CC=CC=C3OC)[2H])[2H]

JWH 250-d5 is a deuterium-labeled form of JWH 250, a synthetic cannabinoid used in research to study cannabinoid receptors and their effects. The deuterium labeling enhances its application in mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy, allowing for accurate tracking and quantification of the compound in biological and chemical studies. This labeled compound is valuable for pharmacokinetic research, studying receptor interactions, and understanding the metabolic pathways of synthetic cannabinoids. It helps in optimizing analytical methods and improving the reliability of research on cannabinoid-based therapies and their effects.

Reference

1.Huffman, J.W.,Szklennik, P.V.,Almond, A., et al. 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles. Bioorganic & Medicinal Chemistry Letters 15, 4110-4113 (2005).