For research use only. Not for therapeutic Use.
JWH 368 is a (1-<wbr></wbr>naphthoyl)pyrrole cannabinoid (CB) that potently activates both central cannabinoid (CB<sub>1</sub>) and preipheral cannabinoid (CB<sub>2</sub>) receptors (K<sub>i</sub> values of 16 and 9.1 nM, respectively). Its physiological, neurological, and toxicological properties have not been evaluated. This compound is intended for forensic and research applications.
| CAS Number | 914458-31-4 |
| Synonyms | [5-(3-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl]-1-naphthalenyl-methanone |
| Molecular Formula | C26H24FNO |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | [5-(3-fluorophenyl)-1-pentylpyrrol-3-yl]-naphthalen-1-ylmethanone |
| InChI | InChI=1S/C26H24FNO/c1-2-3-6-15-28-18-21(17-25(28)20-11-7-12-22(27)16-20)26(29)24-14-8-10-19-9-4-5-13-23(19)24/h4-5,7-14,16-18H,2-3,6,15H2,1H3 |
| InChIKey | OCOICOMCAJNSCA-UHFFFAOYSA-N |
| SMILES | CCCCCN1C=C(C=C1C2=CC(=CC=C2)F)C(=O)C3=CC=CC4=CC=CC=C43 |
| Reference | 1.Huffman, J.W.,Padgett, L.W.,Isherwood, M.L., et al. 1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: New high affinity ligands for the cannabinoid CB1 and CB2 receptors. Bioorganic & Medicinal Chemistry Letters 16(20), 5432-5435 (2006). |
