JWH 387

• CAT Number: R016650
• CAS Number: 1366067-59-5
• Molecular Formula: C24H22BrNO
• Molecular Weight: 420.35
• Purity: ≥95%
• Synonyms: (4-Bromo-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)methanone
• Storage: -20°C
• IUPAC Name: (4-bromonaphthalen-1-yl)-(1-pentylindol-3-yl)methanone
• InChI: InChI=1S/C24H22BrNO/c1-2-3-8-15-26-16-21(19-11-6-7-12-23(19)26)24(27)20-13-14-22(25)18-10-5-4-9-17(18)20/h4-7,9-14,16H,2-3,8,15H2,1H3
• InChIKey: GRWSWDKSCZKGSY-UHFFFAOYSA-N
• SMILES: CCCCCN1C=C(C2=CC=CC=C21)C(=O)C3=CC=C(C4=CC=CC=C43)Br

JWH 387(CAT: R016650) is a synthetic cannabinoid from the naphthoylindole family, developed for research purposes. It acts as a potent agonist of the cannabinoid receptors CB1 and CB2, with a stronger affinity for CB1 receptors, which are primarily found in the brain. Due to its interaction with these receptors, JWH 387 mimics the effects of Δ9-tetrahydrocannabinol (THC), the active compound in cannabis, producing psychoactive and physiological effects. Synthetic cannabinoids like JWH 387 have been explored in research for their potential therapeutic applications, but they are also associated with significant health risks due to their potency and unpredictable effects. Many compounds in this class, including JWH 387, have been banned in various countries due to concerns over safety and misuse.