JYL-79

For research use only. Not for therapeutic Use.

  • CAT Number: I029927
  • CAS Number: 289902-64-3
  • Molecular Formula: C26H36N2O4S
  • Molecular Weight: 472.64
  • Purity: 98%
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JYL-79(CAT: I029927) is a potent and selective vanilloid receptor 1 (VR1) agonist, also known as the transient receptor potential vanilloid 1 (TRPV1) receptor. TRPV1 is a non-selective cation channel primarily involved in the detection and regulation of pain, heat, and inflammatory stimuli. By activating TRPV1, JYL-79 induces calcium influx in sensory neurons, mimicking the effects of capsaicin and contributing to pain signaling and thermal sensation. JYL-79 is widely used in pain research to study nociceptive pathways and explore potential therapies for conditions like chronic pain, neuropathic pain, and inflammatory disorders.


CAS Number 289902-64-3
Synonyms

JYL-79; JYL 79; JYL79;

Molecular Formula C26H36N2O4S
Purity 98%
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name 2,2-Dimethyl-propanoic acid 3-(3,4-dimethylphenyl)-2-[[[[[(4-hydroxy-3-methoxyphenyl)methyl]amino]thioxomethyl]amino]methyl]propyl ester
InChI InChI=1S/C26H36N2O4S/c1-17-7-8-19(11-18(17)2)12-21(16-32-24(30)26(3,4)5)15-28-25(33)27-14-20-9-10-22(29)23(13-20)31-6/h7-11,13,21,29H,12,14-16H2,1-6H3,(H2,27,28,33)
InChIKey KDYVIORLSJSMTG-UHFFFAOYSA-N
SMILES CC(C)(C)C(OCC(CNC(NCC1=CC=C(O)C(OC)=C1)=S)CC2=CC=C(C)C(C)=C2)=O

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