For research use only. Not for therapeutic Use.
JYL-79 is a vanilloid receptor (VR1) agonist.
| Catalog Number | I029927 |
| CAS Number | 289902-64-3 |
| Synonyms | JYL-79; JYL 79; JYL79; |
| Molecular Formula | C26H36N2O4S |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 2,2-Dimethyl-propanoic acid 3-(3,4-dimethylphenyl)-2-[[[[[(4-hydroxy-3-methoxyphenyl)methyl]amino]thioxomethyl]amino]methyl]propyl ester |
| InChI | InChI=1S/C26H36N2O4S/c1-17-7-8-19(11-18(17)2)12-21(16-32-24(30)26(3,4)5)15-28-25(33)27-14-20-9-10-22(29)23(13-20)31-6/h7-11,13,21,29H,12,14-16H2,1-6H3,(H2,27,28,33) |
| InChIKey | KDYVIORLSJSMTG-UHFFFAOYSA-N |
| SMILES | CC(C)(C)C(OCC(CNC(NCC1=CC=C(O)C(OC)=C1)=S)CC2=CC=C(C)C(C)=C2)=O |
| Reference | 1: Czikora Á, Lizanecz E, Bakó P, Rutkai I, Ruzsnavszky F, Magyar J, Pórszász R, Kark T, Facskó A, Papp Z, Édes I, Tóth A. Structure-activity relationships of vanilloid receptor agonists for arteriolar TRPV1. Br J Pharmacol. 2012 Mar;165(6):1801-1812. doi: 10.1111/j.1476-5381.2011.01645.x. PubMed PMID: 21883148; PubMed Central PMCID: PMC3372831. |
