For research use only. Not for therapeutic Use.
K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C extracted from patent WO 2014152588 A1.
IC50 value:
Target: K-ras G12C inhibitor
| Catalog Number | I002111 |
| CAS Number | 1629265-17-3 |
| Synonyms | 1-[4-[2-[4-chloro-5-(2-chlorophenyl)-2-methoxyanilino]acetyl]piperazin-1-yl]prop-2-en-1-one |
| Molecular Formula | C22H23Cl2N3O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C22H23Cl2N3O3/c1-3-21(28)26-8-10-27(11-9-26)22(29)14-25-19-12-16(18(24)13-20(19)30-2)15-6-4-5-7-17(15)23/h3-7,12-13,25H,1,8-11,14H2,2H3 |
| InChIKey | ZJWLFLPGQCYBSE-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C(C(=C1)Cl)C2=CC=CC=C2Cl)NCC(=O)N3CCN(CC3)C(=O)C=C |
