K145 hydrochloride

• CAT Number: I001741
• CAS Number: 1449240-68-9
• Molecular Formula: C18H24N2O3S • HCl
• Molecular Weight: 384.90
• Purity: ≥95%
• Synonyms: (Z)-3-(2-aminoethyl)-5-(3-(4-butoxyphenyl)propylidene)thiazolidine-2,4-dione hydrochloride
• Target: Apoptosis
• Solubility: 10 mM in DMSO
• Storage: Store at -20℃
• IC50: 4.3 uM
• IUPAC Name: (5Z)-3-(2-aminoethyl)-5-[3-(4-butoxyphenyl)propylidene]-1,3-thiazolidine-2,4-dione;hydrochloride
• InChI: InChI=1S/C18H24N2O3S.ClH/c1-2-3-13-23-15-9-7-14(8-10-15)5-4-6-16-17(21)20(12-11-19)18(22)24-16;/h6-10H,2-5,11-13,19H2,1H3;1H/b16-6-
• InChIKey: HADFDMGQKBGVAV-NKBLJONXSA-N
• SMILES: CCCCOC1=CC=C(C=C1)CC/C=C\2/C(=O)N(C(=O)S2)CCN.Cl

K145 Hydrochloride（Cat No.:I001741）is a potent and selective inhibitor of the protein kinase CK2, a key regulator of cell proliferation, survival, and apoptosis. By targeting CK2, K145 Hydrochloride shows promise in disrupting tumor growth and modulating various signaling pathways involved in cancer progression. Its ability to inhibit CK2-mediated phosphorylation makes it a valuable tool in cancer research, particularly for exploring therapeutic strategies aimed at inhibiting oncogenic pathways. K145 Hydrochloride is essential for targeted molecular investigations and drug development.