For research use only. Not for therapeutic Use.
K145 is a selective, substrate-competitive and orally active sphingosine kinase-2 (SphK2) inhibitor with an IC50 of 4.3 µM and a Ki of 6.4 µM in biochemical assays.
| Catalog Number | I001182 |
| CAS Number | 1309444-75-4 |
| Molecular Formula | C18H24N2O3S |
| Purity | ≥95% |
| Storage | 3 years -20°C powder |
| SMILES | CCCCOC1=CC=C(CCC=C2/SC(=O)N(CCN)C2=O)C=C1 |
| Reference | [1] Liu K, et al. PLoS One. 2013;8(2):e56471. |
