K145

• CAT Number: I001182
• CAS Number: 1309444-75-4
• Molecular Formula: C18H24N2O3S
• Molecular Weight: 348.46
• Purity: ≥95%
• Storage: 3 years -20°C powder
• SMILES: CCCCOC1=CC=C(CCC=C2/SC(=O)N(CCN)C2=O)C=C1

K145 is a selective, substrate-competitive and orally active sphingosine kinase-2 (SphK2) inhibitor with an IC50 of 4.3 µM and a Ki of 6.4 µM in biochemical assays.

Reference

[1] Liu K, et al. PLoS One. 2013;8(2):e56471.