K579

For research use only. Not for therapeutic Use.

  • CAT Number: I010633
  • CAS Number: 440100-64-1
  • Molecular Formula: C17H24N6O
  • Molecular Weight: 328.41
  • Purity: ≥95%
Inquiry Now

K579 is a potent and orally active dipeptidyl peptidase IV inhibitor. K579 inhibits the blood glucose elevation. K579 increases the plasma insulin and active forms of glucagon-like peptide-1 (GLP-1). K579 has the potential for the research of diabetic[1].


Catalog Number I010633
CAS Number 440100-64-1
Synonyms

(2S)-1-[2-[(4-methyl-1-pyrimidin-2-ylpiperidin-4-yl)amino]acetyl]pyrrolidine-2-carbonitrile

Molecular Formula C17H24N6O
Purity ≥95%
InChI InChI=1S/C17H24N6O/c1-17(21-13-15(24)23-9-2-4-14(23)12-18)5-10-22(11-6-17)16-19-7-3-8-20-16/h3,7-8,14,21H,2,4-6,9-11,13H2,1H3/t14-/m0/s1
InChIKey JERPHRNGJBSFAP-AWEZNQCLSA-N
SMILES CC1(CCN(CC1)C2=NC=CC=N2)NCC(=O)N3CCCC3C#N
Reference

[1]. Takasaki K,et al. K579, a slow-binding inhibitor of dipeptidyl peptidase IV, is a long-acting hypoglycemic agent. Eur J Pharmacol. 2004 Feb 23;486(3):335-42.
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