Kanamycin A

• CAT Number: I011452
• CAS Number: 59-01-8
• Molecular Formula: C18H36N4O11
• Molecular Weight: 484.50
• Purity: ≥95%
• Synonyms: O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine
• Target: Antibiotic
• Solubility: Soluble in DMSO
• Storage: Store at -20°C
• IUPAC Name: (2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol
• InChI: InChI=1S/C18H36N4O11/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17/h4-18,23-29H,1-3,19-22H2/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-/m1/s1
• InChIKey: SBUJHOSQTJFQJX-NOAMYHISSA-N
• SMILES: C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)N)O)N

Kanamycin A（Cat No.:I011452）is an aminoglycoside antibiotic widely used in microbiological research and clinical applications for its broad-spectrum activity against Gram-negative and Gram-positive bacteria. It inhibits protein synthesis by binding to the bacterial ribosome, preventing translation and leading to bacterial cell death. Kanamycin A is commonly employed in laboratory settings for bacterial culture selection and resistance studies. Despite its effectiveness, its use is limited by potential nephrotoxicity and ototoxicity, especially in prolonged treatments. It is commonly used in research focused on antibiotic resistance and bacterial pathogenesis.