KCC-07

• CAT Number: I014967
• CAS Number: 315702-75-1
• Molecular Formula: C₁₄H₁₁N₃OS
• Molecular Weight: 269.32
• Purity: ≥95%
• Target: DNA Alkylator/Crosslinker

KCC-07 (CAT: I014967) is a potent and selective inhibitor of MBD2 (methyl-CpG-binding domain protein 2). MBD2 is a protein involved in recognizing and binding to methylated DNA, playing a role in epigenetic gene regulation. By inhibiting MBD2, KCC-07 modulates the interactions between MBD2 and methylated DNA, potentially altering gene expression patterns. Its selectivity and brain-penetrant properties make KCC-07 a promising compound for studying the role of MBD2 in various biological processes, including neurological disorders and cancer.

Reference

[1]. Dan Zhu, et al. BAI1 Suppresses Medulloblastoma Formation by Protecting p53 From Mdm2-Mediated Degradation. Cancer Cell. 2018 Jun 11;33(6):1004-1016.e5.