KDM5-C70

• CAT Number: I007490
• CAS Number: 1596348-32-1
• Molecular Formula: C17H28N4O3
• Molecular Weight: 336.44
• Purity: ≥95%
• Synonyms: KDM5-C70; KDM5C70; KDM5 C70.;ethyl 2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinate
• Target: Histone Demethylase
• Solubility: Soluble in DMSO
• Storage: 0 - 4°C for short term , or -20°C for long term.
• IUPAC Name: ethyl 2-[[[2-[2-(dimethylamino)ethyl-ethylamino]-2-oxoethyl]amino]methyl]pyridine-4-carboxylate
• InChI: InChI=1S/C17H28N4O3/c1-5-21(10-9-20(3)4)16(22)13-18-12-15-11-14(7-8-19-15)17(23)24-6-2/h7-8,11,18H,5-6,9-10,12-13H2,1-4H3
• InChIKey: WCILOMUUNVPIKQ-UHFFFAOYSA-N
• SMILES: CCN(CCN(C)C)C(=O)CNCC1=NC=CC(=C1)C(=O)OCC

KDM5-C70(CAT: I007490) is a potent and selective inhibitor of lysine demethylase 5 (KDM5), a family of histone demethylases involved in epigenetic regulation. By targeting KDM5 enzymes, this compound modulates histone methylation levels, making it a valuable tool for studying gene expression and chromatin dynamics. KDM5-C70 is widely used in cancer research, as KDM5 overexpression is implicated in tumor progression, drug resistance, and stem cell maintenance. Its high specificity and robust activity make it suitable for in vitro and in vivo studies, supporting the development of epigenetic-based therapeutic strategies for cancer and other diseases linked to dysregulated gene expression.