For research use only. Not for therapeutic Use.
KH-4-43 (Cat No.: I040178 ) is a small molecule inhibitor that targets the protein-protein interactions between key regulatory factors involved in cancer cell proliferation and survival. It is primarily studied for its ability to disrupt signaling pathways related to cell cycle regulation and apoptosis. KH-4-43 has shown potential in preclinical studies as an anti-cancer agent, particularly for tumors that exhibit dysregulated cell growth and resistance to standard therapies. Ongoing research is focused on evaluating its efficacy and mechanism of action in various cancer models.
CAS Number | 2813310-07-3 |
Synonyms | 3-[1-(4-chlorophenyl)pyrazol-4-yl]-7,8-dihydroxy-2-(trifluoromethyl)chromen-4-one |
Molecular Formula | C19H10ClF3N2O4 |
Purity | ≥95% |
InChI | InChI=1S/C19H10ClF3N2O4/c20-10-1-3-11(4-2-10)25-8-9(7-24-25)14-15(27)12-5-6-13(26)16(28)17(12)29-18(14)19(21,22)23/h1-8,26,28H |
InChIKey | KDPAGFLLKCODNF-UHFFFAOYSA-N |
SMILES | C1=CC(=CC=C1N2C=C(C=N2)C3=C(OC4=C(C3=O)C=CC(=C4O)O)C(F)(F)F)Cl |
Reference | [1]. Wu K, et al. Targeting Cullin-RING E3 Ubiquitin Ligase 4 by Small Molecule Modulators. J Cell Signal. 2021;2(3):195-205. |