For research use only. Not for therapeutic Use.
KM02894 is an inhibitor of glutamate release. Cancer cells release high levels of glutamate, which disrupts normal bone turnover and may lead to cancer-induced bone pain. KM02894 can be used for cancer related research[1].
Catalog Number | I040842 |
CAS Number | 116850-74-9 |
Synonyms | 1-methyl-3-(thiophene-2-carbonylamino)thiourea |
Molecular Formula | C7H9N3OS2 |
Purity | ≥95% |
InChI | InChI=1S/C7H9N3OS2/c1-8-7(12)10-9-6(11)5-3-2-4-13-5/h2-4H,1H3,(H,9,11)(H2,8,10,12) |
InChIKey | SYXUJKFYUBHYNO-UHFFFAOYSA-N |
SMILES | CNC(=S)NNC(=O)C1=CC=CS1 |
Reference | [1]. Fazzari J, et.al. Inhibitors of glutamate release from breast cancer cells; new targets for cancer-induced bone-pain. Sci Rep. 2015 Feb 11;5:8380. |