For research use only. Not for therapeutic Use.
KM91104, a cell-permeable V-ATPase inhibitor, specifically targets the a3-b2 subunits of V-ATPase[1].
Catalog Number | R040343 |
CAS Number | 304481-60-5 |
Synonyms | 3,4-dihydroxy-N-[(E)-(2-hydroxyphenyl)methylideneamino]benzamide |
Molecular Formula | C14H12N2O4 |
Purity | ≥95% |
InChI | InChI=1S/C14H12N2O4/c17-11-4-2-1-3-10(11)8-15-16-14(20)9-5-6-12(18)13(19)7-9/h1-8,17-19H,(H,16,20)/b15-8+ |
InChIKey | GWVYHPUGEQGQSF-OVCLIPMQSA-N |
SMILES | C1=CC=C(C(=C1)C=NNC(=O)C2=CC(=C(C=C2)O)O)O |
Reference | [1]. Marrone G, et al. The adenosine monophosphate-activated protein kinase-vacuolar adenosine triphosphatase-pH axis: A key regulator of the profibrogenic phenotype of human hepatic stellate cells. Hepatology. 2018;68(3):1140-1153. [2]. Göttle P, et al. Rescuing the negative impact of human endogenous retrovirus envelope protein on oligodendroglial differentiation and myelination. Glia. 2019;67(1):160-170. doi:10.1002/glia.23535 |