For research use only. Not for therapeutic Use.
Kobe2601 is a Kobe0065 (HY-15716) analogue. Kobe2601 can be used to probe the Kobe family of compounds’ mechanism of action[1].
| Catalog Number | R017255 |
| CAS Number | 316151-68-5 |
| Synonyms | 1-(2,4-dinitroanilino)-3-(4-fluorophenyl)thiourea |
| Molecular Formula | C13H10FN5O4S |
| Purity | ≥95% |
| InChI | InChI=1S/C13H10FN5O4S/c14-8-1-3-9(4-2-8)15-13(24)17-16-11-6-5-10(18(20)21)7-12(11)19(22)23/h1-7,16H,(H2,15,17,24) |
| InChIKey | XAWWYTYFOCONCK-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1NC(=S)NNC2=C(C=C(C=C2)[N+](=O)[O-])[N+](=O)[O-])F |
| Reference | [1]. Shima F, et al. In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8182-7. |
