For research use only. Not for therapeutic Use.
KRAS G12C inhibitor 19 is a potent inhibitor of KRAS G12C. KRAS G12C inhibitor 19 significantly inhibits tumor growth (extracted from patent WO2021118877A1)[1].
| Catalog Number | I045323 |
| CAS Number | 2771246-13-8 |
| Synonyms | 4-[(13aS)-10-chloro-8-fluoro-6-oxo-2-prop-2-enoyl-1,3,4,12,13,13a-hexahydropyrazino[2,1-d][1,5]benzoxazocin-9-yl]-2-amino-7-fluoro-1-benzothiophene-3-carbonitrile |
| Molecular Formula | C25H19ClF2N4O3S |
| Purity | ≥95% |
| InChI | InChI=1S/C25H19ClF2N4O3S/c1-2-18(33)31-6-7-32-12(11-31)5-8-35-22-14(25(32)34)9-17(28)20(21(22)26)13-3-4-16(27)23-19(13)15(10-29)24(30)36-23/h2-4,9,12H,1,5-8,11,30H2/t12-/m0/s1 |
| InChIKey | OZUPICRWMLEFCS-LBPRGKRZSA-N |
| SMILES | C=CC(=O)N1CCN2C(C1)CCOC3=C(C(=C(C=C3C2=O)F)C4=C5C(=C(SC5=C(C=C4)F)N)C#N)Cl |
| Reference | [1]. Serge Louis Boulet, et al. Kras g12c inhibitors. Patent WO2021118877A1. |
