For research use only. Not for therapeutic Use.
KRpep-2d is a K-Ras(G12D) selective inhibitory cyclic peptide with selectivity against wild-type (WT) K-Ras and the K-Ras(G12C) mutant. The IC50 value is 1.6 nM.
| Catalog Number | I047322 |
| CAS Number | 2098181-84-9 |
| Molecular Formula | C108H182N44O25S2 |
| Purity | ≥95% |
| Storage | 3 years-20°Cpowder |
| SMILES | CCC(C)C1NC(=O)C(CC2=CC=C(O)C=C2)NC(=O)C(CC(C)C)NC(=O)C3CCCN3C(=O)C(CSSCC(NC(=O)C(NC(=O)C4CCCN4C(=O)C(CC(O)=O)NC(=O)C(CC5=CC=C(O)C=C5)NC(=O)C(CO)NC1=O)C(C)C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CCCNC(N)=N)C(=O)N |
| Reference | [1] Satoshi Sogabe, et al. ACS Med Chem Lett. 2017, 8:732−736. |
