For research use only. Not for therapeutic Use.
KSI-3716 (Cat.No:I020007) is a small molecule inhibitor that targets the enzyme 3-ketosteroid Δ^1-dehydrogenase (KSI), which is involved in the biosynthesis of androgens and estrogens. By inhibiting KSI, KSI-3716 disrupts steroid hormone synthesis, making it a potential therapeutic option for hormone-dependent cancers such as breast and prostate cancer. Further research is ongoing to explore its efficacy and safety profile.
| Catalog Number | I020007 |
| CAS Number | 1151813-61-4 |
| Molecular Formula | C₁₇H₁₁BrCl₂N₂O₂ |
| Purity | ≥95% |
| Target | Autophagy |
| IUPAC Name | 3-acetyl-8-bromo-5-chloro-2-(4-chloroanilino)-1H-quinolin-4-one |
| InChI | 1S/C17H11BrCl2N2O2/c1-8(23)13-16(24)14-12(20)7-6-11(18)15(14)22-17(13)21-10-4-2-9(19)3-5-10/h2-7H,1H3,(H2,21,22,24) |
| InChIKey | URUPDOIKTMCJNA-UHFFFAOYSA-N |
| SMILES | CC(=O)C1=C(NC2=C(C=CC(=C2C1=O)Cl)Br)NC3=CC=C(C=C3)Cl |
| Reference | [1]. Jeong KC, et al. Intravesical instillation of c-MYC inhibitor KSI-3716 suppresses orthotopic bladder tumor growth. J Urol. 2014 Feb;191(2):510-8. |
