KSI-3716

• CAT Number: I020007
• CAS Number: 1151813-61-4
• Molecular Formula: C₁₇H₁₁BrCl₂N₂O₂
• Molecular Weight: 426.09
• Purity: ≥95%
• Target: Autophagy

KSI-3716 (Cat.No:I020007) is a small molecule inhibitor that targets the enzyme 3-ketosteroid Δ^1-dehydrogenase (KSI), which is involved in the biosynthesis of androgens and estrogens. By inhibiting KSI, KSI-3716 disrupts steroid hormone synthesis, making it a potential therapeutic option for hormone-dependent cancers such as breast and prostate cancer. Further research is ongoing to explore its efficacy and safety profile.

Reference

[1]. Jeong KC, et al. Intravesical instillation of c-MYC inhibitor KSI-3716 suppresses orthotopic bladder tumor growth. J Urol. 2014 Feb;191(2):510-8.