KT-531

• CAT Number: I047323
• CAS Number: 2490284-18-7
• Molecular Formula: C17H14F4N2O4S
• Molecular Weight: 418.36
• Purity: ≥95%
• Storage: 3 years -20°C powder
• SMILES: ONC(=O)C1=CC=C(CN(C2CC2)[S;v6](=O)(=O)C3=C(F)C(=C(F)C(=C3)F)F)C=C1

KT-531 (KT531) is a potent, selective HDAC6 inhibitor with IC50 of 8.5 nM, displays 39-fold selectivity over other HDAC isoforms.

Reference

[1] Toutah K, et al. J Med Chem. 2021 Jun 24;64(12):8486-8509.